This is where having a good crew comes into play, as they are the ones that you charge to get the word out in that nieghborhood. I will have them throw a couple doorhangers out to potencial customers or stop and talk to the wife out getting the kids off to school at the bus stop. It all about being clean, neat, and the highest level of Courtesy. Keep these elements in the fore front and that one secluded property turns into a cash cow.
And that is how you deal/think of those properties, not as a hinderance but as an opertunity.